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Free Test Prep PCAT Exam Questions

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  • Test Prep PCAT Exam Questions
  • Provided By: Test Prep
  • Exam: Pharmacy College Admission Test
  • Certification: Test Prep Certifications
  • Total Questions: 285
  • Updated On: Sep 26, 2024
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  • Question 1
    • If a substance has a constant half-life of 10 weeks, how many grams of a 12 g sample would remain after 30
      weeks?

      Answer: D
  • Question 2
    • For most Americans, the words “Alzheimer’s disease” (AD) – often mispronounced purposefully or accidentally
      as “old timers’ disease” – signify devastating memory loss and stigma. The information about AD – often
      learned solely through the media – may lead individuals to believe that AD is inevitable (it isn’t), and possibly
      think that all AD patients receive poor care (there are many remarkably good AD units). Many individuals may
      envision a future burdened with more dementia patients and fewer societal resources to help support them (a
      real possibility). In general, pharmacists are well aware of what AD is and isn’t. AD is complex and relentlessly
      progressive; it affects patients, loved ones, and caregivers adversely. Pharmacists can provide pertinent
      information about AD’s myths, realities, and available symptomatic treatments. AD’s harbinger is language
      difficulties, which include aphasia (language disturbance), apraxia (inability to carry out motor functions), and
      agnosia (failure to recognize or identify objects). Consequently, those with AD will often create new words for
      items. They may call a pencil a “list writer,” or a key a “door turner.” Clinicians stage AD as mild, moderate, or
      severe depending on the patient’s cognitive and memory impairment, communication problems, personality
      changes, behavior, and loss of control of bodily functions. People often dismiss mild AD as normal cognitive
      decline or senility – in other words, “normal” aging. For this reason, most people don’t seek treatment and are
      diagnosed in the late-mild to early-moderate stage. In the severe stage, difficulty swallowing elevates the risk of
      aspiration pneumonia, which often marks the beginning of the downward spiral that ultimately ends with death;
      AD has no cure. A handful of pharmacologic treatments – acetylcholinesterase inhibitors and N-methyl-Daspartate antagonists – alter the decline trajectory. These treatments slow disease progression, enhance
      cognitive function, delay cognitive decline, and decrease disruptive behaviors. Not all patients respond to these
      medications, but experts generally believe that those who do will show mild to moderate improvements for 6
      months to a year. Although the drugs’ effects are short-lived, they improve patients’ quality of life and briefly
      enable independence. Determining when medications stop providing a therapeutic benefit and should be
      discontinued is challenging. Clinicians use various methods to monitor decline, including mental status tools,
      patient self-report, and loved ones’ observations. Most clinicians continue drug treatment if the patient seems to
      tolerate the medication well, can afford it, and if there seems to be a benefit. With disease progression, specific
      behavioral symptoms including depression, agitation, hallucinations, and sleep disturbances become concerns.
      Antianxiety drugs, antipsychotics, and antidepressants are sometimes used to alleviate symptoms, but effective
      behavioral strategies are much preferred.
      The author’s attitude toward Alzheimer’s disease is best summarized by which of the following?

      Answer: B
  • Question 3
    • A virus contains all of the following except?

      Answer: A
  • Question 4
    • When blood flow to human tissue is interrupted, the lack of sufficient blood supply is called ischemia. If
      ischemia is not restored quickly, the affected tissue may undergo a process called infarction, which involves a
      series of chemical changes that damage the tissue. The lack of blood supply results in lack of oxygen, and thus
      lactic acidosis. Mitochondrial dysfunction results. Microscopic examination and chemical analysis of ischemic
      cells reveal membrane degeneration, excessive calcium (Ca+) inside the cell, and free radical formation,
      accompanied by a reactive inflammation and free fatty acid formation. A research experiment is designed to
      evaluate the response of infarcted tissue to intra-arterial administration of an antioxidant. Preliminary results
      demonstrate that follow-up evaluation of tissue exposed to intra-arterial antioxidant injection resulted, on
      average, in a smaller area of infarcted tissue after seven days when compared to controls without exposure to
      the antioxidant. It was noted that 70% of the patients who demonstrated smaller areas of infarction also had a
      notable decease in edema of the ischemic tissue lasting about 6 to 10 hours after injection.
      Which of the following chemical moieties forms the backbone of DNA?

      Answer: D
  • Question 5
    • What would be the result of increasing the number of nucleophiles in a SN1 reaction? 

      Answer: D
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